General Cell Based Assays
Eurofins Discoverx cAMP Hunter eXpress CRHR2 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0048E2CP2L)
The cAMP Hunter CRHR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CRH, sauvagine) based activation of CRHR2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CRHR2, a naturally Gs coupled GPCR. Upon activation of CRHR2, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ABclonal Technology HRH3 Rabbit pAb
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
Cusabio Technology LLC superoxide dismutase 1
This kit detects SOD1 in serum plasma cell culture supernates and tissue homogenates offering a quantitative measurement range of 15 6 pg/mL to 1000 pg/mL with a sensitivity of 3 9 pg/mL Designed for efficient analysis it employs a sandwich ELISA methodology requiring a sample volume of 50-100 L and delivering results within 1-5 hours The assay utilizes absorbance measurement at 450 nm to ensure accurate detection and quantification of SOD1 across diverse biological samples making it suitable for research applications demanding high precision and reliability in measuring soluble superoxide dismutase 1 levels
American Research Products Inc NFAT3 Transcription Factor Activity Assay
NFAT3 Transcription Factor Activity Assay
Cayman Chemical RXR aRetInoId X RECPTR a 100uL
An affinity probe for ganglioside GM3 binding partners
Eurofins Discoverx PathHunter eXpress SSTR2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0181E2CP0M)
The PathHunter SSTR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. somatostatin) based activation of SSTR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR2 and EA-tagged β-Arrestin-2. Activation of SSTR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress PPYR1 (NPY4R) CHO-K1 GPCR Assay, 10-Plate Kit. (95-0087E2CP2L)
The cAMP Hunter PPYR1 (NPY4R) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. pancreatic polypeptide, peptide YY) based activation of PPYR1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type PPYR1, a naturally Gi/Go coupled GPCR. Upon activation of PPYR1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx AssayComplete Thawing Reagent T8, 100. (92-4108TR)
AssayComplete Thawing Reagent T8 is an optimized thawing reagent for revival and recovery of Eurofins DiscoverX cell lines. This reagent ensures optimal post-thaw viability, recovery and assay performance upon thawing. This product is provided as a bottle of 100 mL. Please refer to cell line specific datasheet to determine the recommended thawing reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Meso Scale Discovery R-PLEX Human ADAM17 ASYQP
The R-PLEX Human ADAM17 Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures active ADAM17 in human serum plasma and cell culture supernatants The assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity and a broad dynamic range This kit includes a 96-well plate coated with capture antibody detection antibody Read Buffer and calibrator The assay can detect ADAM17 levels between 0 3-1000 pg/mL and requires only 50 L of sample
Eurofins Discoverx PathHunter eXpress CCR10 Activated GPCR Internalization Assay, 10pl Kit. (93-0783E3CP5L)
The PathHunter CCR10 Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CCR10 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CCR10. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CCR10-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.